Development and Evaluation of Microneedle Arrays for Ocular Drug Delivery
Development and Evaluation of Microneedle Arrays for Ocular Drug Delivery
About the Project Minimally invasive microneedles (MNs) offer unique opportunities to address current challenges in the effective management of ocular disorders, such as age-related macular degeneration and diabetic retinopathy. There … Read More Read More
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Self-Assembling Peptide Nanomaterials for Targeted Ocular Drug Delivery
Self-Assembling Peptide Nanomaterials for Targeted Ocular Drug Delivery
About the Project Self-assembling peptide-based hydrogels (SAPH) are composed of short peptide sequences, typically consisting of 5 to 20 amino acids, which undergo spontaneous self-assembly into three-dimensional networks under physiological … Read More Read More
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4D printed Biomaterials in cancer therapeutics
4D printed Biomaterials in cancer therapeutics
About the Project According to WHO, cancer is the second leading cause of death worldwide, with nearly 1 in 6 deaths been due to cancer. The principal modes of cancer … Read More Read More
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Design and Assessment of Innovative Long-Acting Drug Delivery System
Design and Assessment of Innovative Long-Acting Drug Delivery System
About the Project Current clinical therapies often rely on intermittent drug administration, such as frequent oral tablets or injections, as seen in diabetes management. However, drug concentrations in the bloodstream … Read More Read More
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Innovative Drug Delivery Systems for Ocular Therapies: Micro- and Nano-Formulation Approaches
Innovative Drug Delivery Systems for Ocular Therapies: Micro- and Nano-Formulation Approaches
About the Project Ocular drug delivery presents one of the greatest challenges in pharmaceutical science, largely due to the eye’s unique anatomy, which limits drug permeation to the intended site … Read More Read More
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Development of silicone-based personal lubricant products containing antiretroviral drugs for prevention of sexual acquisition of HIV infection
Development of silicone-based personal lubricant products containing antiretroviral drugs for prevention of sexual acquisition of HIV infection
About the Project Three drug products are now available to prevent HIV prevention: Truvada®/ Descovy®—daily oral pills containing the antiretroviral drugs emtricitabine and tenofovir DapiRing®—a vaginal ring device release dapivirine … Read More Read More
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Peptide-based nanoparticles for brain-targeted gene delivery to treat neurodegenerative diseases.
Peptide-based nanoparticles for brain-targeted gene delivery to treat neurodegenerative diseases.
About the Project The aim of this project is to engineer brain-targeted nanoparticles to efficiently deliver novel therapeutic agents for the treatment of neurodegenerative diseases (e.g., Parkinson’s and Alzheimer’s Disease), … Read More Read More
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Combinations of bacteriophages and cold plasma for biofilm biocontrol
Combinations of bacteriophages and cold plasma for biofilm biocontrol
About the Project The ongoing antimicrobial resistance crisis has incentivised research into alternative antibacterial and antibiofilm agents. One of them is cold plasma and plasma-activated water (PAW), which is produced … Read More Read More
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Investigating new excipients to improve ionizable lipid nanoparticles’ endosomal escape and enhance gene expression
Investigating new excipients to improve ionizable lipid nanoparticles’ endosomal escape and enhance gene expression
About the Project Nucleic acids have the potential to treat a wide range of diseases, from cancer to hereditary conditions. However, their clinical use has been limited due to unfavorable … Read More Read More
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Non-thermal irreversible electroporation to treat advanced cancer
Non-thermal irreversible electroporation to treat advanced cancer
About the Project Irreversible electroporation (IRE) is an innovative non-thermal ablation technique that induces cell death by creating permanent cell membrane lysis through a short, high-voltage direct electrical current. IRE … Read More Read More
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