Search
Clear all filters
DP Rebecca Shepherd
4-year PhD Studentship: Creating patient-specific retinal organoids from human induced pluripotent stem cells for in vitro simulation of uveitis
4-year PhD Studentship: Creating patient-specific retinal organoids from human induced pluripotent stem cells for in vitro simulation of uveitis

About the Project Uveitis, although uncommon, is a notable cause of visual impairment and blindness. Uveitis encompasses a range of conditions driven by both innate autoinflammatory and adaptive autoimmune CD4 … Read More Read More

Categories:
DP Rebecca Shepherd
4-year PhD Studentship: Modelling and economic evaluation of Hepatitis B virus elimination in Georgia
4-year PhD Studentship: Modelling and economic evaluation of Hepatitis B virus elimination in Georgia

About the Project A national serosurvey in Georgia in 2015 identified that the chronic prevalence of Hepatitis C virus (HCV) in adults in the country was 5.4%, and chronic infection … Read More Read More

Categories:
DP Rebecca Shepherd
4-year PhD Studentship: Exploring Parkinson’s disease subtypes using data driven approaches applied to prospective cohorts
4-year PhD Studentship: Exploring Parkinson’s disease subtypes using data driven approaches applied to prospective cohorts

About the Project Parkinson’s disease is a progressive neurodegenerative disorder characterised by a wide range of motor and non-motor features, for which there is no known cause. There is large … Read More Read More

Categories:
DP Rebecca Shepherd
4-year PhD Studentship: Understanding the role of adiponectin in kidney disease development at a population level
4-year PhD Studentship: Understanding the role of adiponectin in kidney disease development at a population level

About the Project Reduced circulating adiponectin levels are associated with poor outcome in patients with diabetic kidney disease (DKD) (1). Adiponectin has been shown to be protective against the development … Read More Read More

Categories:
DP Rebecca Shepherd
4-year PhD Studentship: The Role of Amyloid Precursor Protein in Prostate Cancer: Lessons Learnt from Alzheimer's Disease
4-year PhD Studentship: The Role of Amyloid Precursor Protein in Prostate Cancer: Lessons Learnt from Alzheimer's Disease

About the Project Prostate cancer(PCa) remains the second most common cancer and the fifth leading cause of cancer death among men worldwide[1]. Whilst current therapies have led to improvements in … Read More Read More

Categories:
DP Rebecca Shepherd
4-year PhD Studentship: Developing tailored solutions to under-recruiting randomised controlled trials: a mixed-methods investigation
4-year PhD Studentship: Developing tailored solutions to under-recruiting randomised controlled trials: a mixed-methods investigation

About the Project Randomised controlled trials (RCTs) drive evidence-based medicine, but they can be resource-intensive and challenging to conduct. One in three RCTs close early, most frequently due to difficulties … Read More Read More

Categories:
DP Rebecca Shepherd
4-year PhD Studentship: Endothelial glycocalyx damage as a therapeutic target in sepsis-associated Acute Kidney Injury
4-year PhD Studentship: Endothelial glycocalyx damage as a therapeutic target in sepsis-associated Acute Kidney Injury

About the Project Sepsis is the leading cause of acute kidney injury (sAKI), associated with high morbidity and mortality.1,2 Unfortunately, there is no treatment for sAKI, current therapies are nonspecific … Read More Read More

Categories: