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DP Jeremy Hunt
Identifying age-related extracellular microenvironment in dental tissues
Identifying age-related extracellular microenvironment in dental tissues

About the Project Periodontal disease is the sixth most globally prevalent age-related disease and a leading cause of tooth loss, significantly impacting quality of life and healthy ageing. According to … Read More Read More

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DP Leandro Oliveira
MRes – Is self-paced performance the key to normalising intensity of interval training across individuals? (Project ID SAS0206)
MRes – Is self-paced performance the key to normalising intensity of interval training across individuals? (Project ID SAS0206)

About the Project High-intensity interval training (HIIT) is a widely employed training methodology known for its effectiveness in improving cardiorespiratory and metabolic fitness, ultimately leading to increased exercise capacity (Buchheit … Read More Read More

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DP Jim Taylor
The epigenomic, transcriptional and diagnostic architecture of neurodevelopmental disorders caused by exposure to maternal infection
The epigenomic, transcriptional and diagnostic architecture of neurodevelopmental disorders caused by exposure to maternal infection

About the Project A fundamental unknown in understanding mechanisms of disease, and therefore improving therapy, is how stressors experienced during critical developmental periods influence the genesis or ‘programming’ of adult … Read More Read More

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DP Aly Hill
Musculoskeletal Ageing and Inflammation Research
Musculoskeletal Ageing and Inflammation Research

About the Project We are seeking talented, motivated students with a passion for research in musculoskeletal ageing and chronic inflammatory diseases (e.g., osteoarthritis and sarcopenia) to join the Musculoskeletal Ageing … Read More Read More

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DP Jim Taylor
Using microRNA inhibitors to boost GABAergic inhibition as a genetic therapy for epilepsy
Using microRNA inhibitors to boost GABAergic inhibition as a genetic therapy for epilepsy

About the Project Epilepsy is a chronic neurological disease characterised by recurrent spontaneous seizures and cognitive co-morbidities. Current small molecule approaches to treating epilepsy are ineffective in a significant portion … Read More Read More

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DP Helen Jacobs-Lewiss
Delivery and misdelivery of outer membrane proteins to the BAM complex using cryoEM
Delivery and misdelivery of outer membrane proteins to the BAM complex using cryoEM

About the Project The BAM complex folds membrane proteins into the outer membrane of Gram-negative bacteria, proteins whose functions are essential for bacterial viability, pathogenicity and virulence. Targeting OMP biogenesis … Read More Read More

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DP Rebecca Shepherd
4-year PhD Studentship: The Role of Amyloid Precursor Protein in Prostate Cancer: Lessons Learnt from Alzheimer's Disease
4-year PhD Studentship: The Role of Amyloid Precursor Protein in Prostate Cancer: Lessons Learnt from Alzheimer's Disease

About the Project Prostate cancer(PCa) remains the second most common cancer and the fifth leading cause of cancer death among men worldwide[1]. Whilst current therapies have led to improvements in … Read More Read More

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DP Jing(静) Wang
Unravelling the Intricacies of Stress Hormone Regulation
Unravelling the Intricacies of Stress Hormone Regulation

About the Project Project Overview: The proopiomelanocortin (POMC) pathway is a crucial signaling cascade involved in regulating various physiological processes, including our response to stress, metabolism, immune function, and pigmentation. … Read More Read More

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