Rebecca ShepherdInvestigation of the extracellular matrix as a regulator of Parkinson’s progression
Investigation of the extracellular matrix as a regulator of Parkinson’s progression
About the Project Parkinson’s is the 2 nd most common neurodegenerative disease, affecting around 1 in 20 people aged over 65. In the UK, the number of affected people is … Read More Read More
Categories:
Jim TaylorGenotypic and phenotypic markers of resistance in Aspergillus fumigatus and their impact on outcomes in chronic pulmonary aspergillosis
Genotypic and phenotypic markers of resistance in Aspergillus fumigatus and their impact on outcomes in chronic pulmonary aspergillosis
About the Project Chronic pulmonary aspergillosis (CPA) is a progressive infection affecting patients with chronic lung disease. It significantly affects quality of life and mortality. Only around 60% respond to … Read More Read More
Categories:4-year PhD Studentship: Repositioning blood pressure lowering drugs to treat Alzheimer’s disease
4-year PhD Studentship: Repositioning blood pressure lowering drugs to treat Alzheimer’s disease
About the Project Elevated blood pressure in mid-life is a risk factor for Alzheimer’s disease (AD). Blood pressure lowering drugs protect against cognitive decline and may slow the progression of … Read More Read More
Categories:
Sergio DiazRepositioning blood pressure lowering drugs to treat Alzheimer’s disease
Repositioning blood pressure lowering drugs to treat Alzheimer’s disease
About the Project Elevated blood pressure in mid-life is a risk factor for Alzheimer’s disease (AD). Blood pressure lowering drugs protect against cognitive decline and may slow the progression of … Read More Read More
Categories:
William MielcarekMolecular mechanisms of pacemaker (sinus node) dysfunction in ageing, heart failure and athletes
Molecular mechanisms of pacemaker (sinus node) dysfunction in ageing, heart failure and athletes
About the Project The heart’s pacemaker, the sinus node, initiates the action potential that causes the heart to beat, and the atrioventricular node conducts the action potential from the atria … Read More Read More
Categories:Characterisation of adrenoceptor and muscarinic receptor subtypes coupled to potassium channels in chondrocytes from bovine cartilage
Characterisation of adrenoceptor and muscarinic receptor subtypes coupled to potassium channels in chondrocytes from bovine cartilage
About the Project Several outward potassium currents have been identified in bovine chondrocytes (review Mobasheri et al. 2012). These include ATP-sensitive and a Calcium-activated potassium currents (Sanches & Lopez-Zapata, 2011). … Read More Read More
Categories:Beat-to-beat modulation of Calcium-induced Calcium release in cardiac muscle
Beat-to-beat modulation of Calcium-induced Calcium release in cardiac muscle
About the Project Contraction in the heart is well known to be dependent on a transient rise in intracellular calcium concentration. This increase in intracellular calcium is due to calcium … Read More Read More
Categories:
Rishikesh GuptaInvestigating the role of oxidative metabolites in joint destruction in osteoarthritis
Investigating the role of oxidative metabolites in joint destruction in osteoarthritis
About the Project We are seeking a motivated researcher to work on a pioneering project investigating the role of oxidative stress in alkaptonuria (AKU) and associated conditions. AKU is a … Read More Read More
Categories:
Zoe LartigauHealth economic evaluation of community acquired pneumonia in the UK
Health economic evaluation of community acquired pneumonia in the UK
About the Project Pneumonia is a common illness that results in over 100,000 hospital admissions per year in the UK. Following hospital treatment for pneumonia, 55% of patients visit their … Read More Read More
Categories:
Rodrigo OsorioMetabolic MRI of paediatric-type diffuse high grade glioma and its response to therapy in vivo
Metabolic MRI of paediatric-type diffuse high grade glioma and its response to therapy in vivo
About the Project Paediatric-type diffuse high grade glioma (PDHGG) is a leading cause of tumour-related death in children and young adults, and novel therapeutic approaches are urgently needed (1). The … Read More Read More
Categories: