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DP Jim Taylor
The epigenomic, transcriptional and diagnostic architecture of neurodevelopmental disorders caused by exposure to maternal infection
The epigenomic, transcriptional and diagnostic architecture of neurodevelopmental disorders caused by exposure to maternal infection

About the Project A fundamental unknown in understanding mechanisms of disease, and therefore improving therapy, is how stressors experienced during critical developmental periods influence the genesis or ‘programming’ of adult … Read More Read More

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DP Farrukh Ali Khan
Helminth products as macrophage “trainers”: a novel tool to induce anti-inflammatory trained immunity
Helminth products as macrophage “trainers”: a novel tool to induce anti-inflammatory trained immunity

About the Project The innate immune system can display characteristics of immunological memory. This phenomenon, termed “trained immunity”, refers to the long-term functional reprogramming of innate immune cells after the … Read More Read More

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DP Niels Madsen
Structural Biology of Host-Parasite Interactions
Structural Biology of Host-Parasite Interactions

About the Project PhD Position in Structural Parasitology A position for a talented and self-motivated PhD student is open in the structural biology group at IOCB Prague lead by Dr. … Read More Read More

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DP Isabell Baker
Development of Naked Mole Rat Colonic Crypt Models to Use in the Search for Bowel Disease Preventatives
Development of Naked Mole Rat Colonic Crypt Models to Use in the Search for Bowel Disease Preventatives

About the Project Diseases affecting the bowel such as colorectal cancer (CRC) and the inflammatory bowel diseases (IBD) ulcerative colitis and Crohn’s disease are major global healthcare challenges in the … Read More Read More

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DP Jim Taylor
Defining the protective effects of a commensal bacterial strain in skin barrier function and protection from disease
Defining the protective effects of a commensal bacterial strain in skin barrier function and protection from disease

About the Project Maintaining a healthy skin barrier is vital for our health. In response to skin wounding, we have a well-orchestrated immune response that heals the breach. Delays in … Read More Read More

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DP Isabell Baker
Identify novel approaches to combat multi drug resistant pathogens
Identify novel approaches to combat multi drug resistant pathogens

About the Project Our research is focused on recalcitrant ESKAPE ( Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species) pathogens; especially hard-to-treat clinical isolates involved … Read More Read More

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DP Martins Sotomayor
Systems immunology and multi-omics approaches to understand protective immunity to human malaria
Systems immunology and multi-omics approaches to understand protective immunity to human malaria

About the Project This PhD project aims to develop and apply computational approaches that integrate systems biology and molecular immunology to understand host-pathogen immunity and predict immune control of malaria. … Read More Read More

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DP Martins Sotomayor
Vaccine Engineering
Vaccine Engineering

About the Project An opportunity exists for a PhD position in vaccine engineering. Vaccines are one of the most effective health care interventions but remain a challenge for many diseases, … Read More Read More

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DP Martins Sotomayor
Molecular Immunology of Malaria
Molecular Immunology of Malaria

About the Project An opportunity exists for a PhD position in the molecular immunology of malaria. The focus of this project will be to apply cutting-edge technologies to understand the … Read More Read More

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