Aly HillExploring the cellular and molecular mechanisms mediating myelin formation, injury and repair in the central nervous system
Exploring the cellular and molecular mechanisms mediating myelin formation, injury and repair in the central nervous system
About the Project We are seeking talented, motivated students with a passion for research on glial cells and their involvement in mechanisms mediating central nervous system development, function and disease … Read More Read More
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Rebecca ShepherdNew Drugs for Brain Tumours: A Locoregional Implant Brain Tumours
New Drugs for Brain Tumours: A Locoregional Implant Brain Tumours
About the Project Next-generation temozolomide derivatives for the treatment of high-grade glioma have been developed at the University of Bradford. This project will optimise an implantable formulation to be deposited … Read More Read More
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Jim TaylorGene-based replacement therapy for hearing loss
Gene-based replacement therapy for hearing loss
About the Project Hearing loss is the most common sensory dysfunction in humans, and it is associated with social isolation and depression. Approximately 1 billion people in the world will … Read More Read More
Categories:New Drugs for Brain Tumours: Prodrugs of Diazopropyne
New Drugs for Brain Tumours: Prodrugs of Diazopropyne
About the Project The propargyl group, introduced to temozolomide-like drugs for brain tumours by our colleagues in Nottingham, shows considerable pre-clinical promise and is anticipated to be a precursor of … Read More Read More
Categories:4-year PhD Studentship: Epilepsy and the ageing brain
4-year PhD Studentship: Epilepsy and the ageing brain
About the Project Our ability to remember ‘where I put my car keys today’ instead of ‘where I put them yesterday’ depends on a computational process called pattern separation. Pattern … Read More Read More
Categories:4-year PhD Studentship: How does pro-angiogenic signalling contribute to the vascular dysfunction observed in the early stages of Alzheimer’s disease, and can this be prevented using existing therapeutics?
4-year PhD Studentship: How does pro-angiogenic signalling contribute to the vascular dysfunction observed in the early stages of Alzheimer’s disease, and can this be prevented using existing therapeutics?
About the Project Vascular dysfunction is now considered an early event in Alzheimer’s disease development (AD)(1,2). Blood-brain barrier (BBB) leakiness is detectable early in pre-clinical AD, which allows an influx … Read More Read More
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Mary Delong3D printing spinal cords
3D printing spinal cords
About the Project Project Overview This project offers an exciting opportunity to use hydrogels and 3D printing to engineer a segment of the spinal cord, which could be further developed … Read More Read More
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Niels MadsenInvestigating the Role of Subcortical Visual Pathways for 'Blindsight' and Gist Perception in Parkinson's Disease Using Multimodal Neuroimaging and Computational Neuroscience
Investigating the Role of Subcortical Visual Pathways for 'Blindsight' and Gist Perception in Parkinson's Disease Using Multimodal Neuroimaging and Computational Neuroscience
About the Project Parkinson's disease (PD) is primarily known as a movement disorder, but emerging evidence suggests that it might also significantly impact visual processing, specifically 'blindsight' and gist perception … Read More Read More
Categories:4-year PhD Studentship: Repositioning blood pressure lowering drugs to treat Alzheimer’s disease
4-year PhD Studentship: Repositioning blood pressure lowering drugs to treat Alzheimer’s disease
About the Project Elevated blood pressure in mid-life is a risk factor for Alzheimer’s disease (AD). Blood pressure lowering drugs protect against cognitive decline and may slow the progression of … Read More Read More
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Sergio DiazRepositioning blood pressure lowering drugs to treat Alzheimer’s disease
Repositioning blood pressure lowering drugs to treat Alzheimer’s disease
About the Project Elevated blood pressure in mid-life is a risk factor for Alzheimer’s disease (AD). Blood pressure lowering drugs protect against cognitive decline and may slow the progression of … Read More Read More
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