Niels MadsenEjecting infection: Understanding how epithelial tissues rid themselves of viral infections by apical extrusion
Ejecting infection: Understanding how epithelial tissues rid themselves of viral infections by apical extrusion
About the Project Background The epithelial tissues of our bodies use physical barriers and innate defences to fight viral infection. When infections establish, tissues can call on the immune system … Read More Read More
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Rebecca Shepherd4-year PhD Studentship: Disentangling the pathways and molecular basis of inverse associations between Alzheimer's disease and cancer
4-year PhD Studentship: Disentangling the pathways and molecular basis of inverse associations between Alzheimer's disease and cancer
About the Project Epidemiological studies and systematic reviews report unexplained inverse associations between risk of developing Alzheimer's disease (AD) and risk of cancer (Shafi, (2016); Zablocka et al (2021)). Survival … Read More Read More
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Amalie JohannsenTranscriptional kinases in cancer and developmental disorders
Transcriptional kinases in cancer and developmental disorders
About the Project Cyclin-dependent kinases (CDKs) are protein kinases performing essential functions in regulation of cell cycle and transcription. Each CDK requires an interaction with a specific cyclin partner for … Read More Read More
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Daisy LyDesigning and evaluating novel nanotherapeutics to enhance the effectiveness of radiotherapy in the treatment of solid cancers.
Designing and evaluating novel nanotherapeutics to enhance the effectiveness of radiotherapy in the treatment of solid cancers.
About the Project One in two cancer patients will receive radiotherapy as part of their treatment. For patients with a localised cancer diagnosis effective radiotherapy represents the best chance of … Read More Read More
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Zoe LartigauShort and long-distance communication in cancer: Feedback regulation of Ras signalling in tumourigenesis and cachexia
Short and long-distance communication in cancer: Feedback regulation of Ras signalling in tumourigenesis and cachexia
About the Project Hamaratoglu Lab studies cell-cell signalling in development and tumourigenesis. We take advantage of outstanding genetic tools in Drosophila, and use larval imaginal discs as model epithelial organs. … Read More Read More
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Lany MichalskyBiological pathways supporting the formation and function of chromatin (Scholarship)
Biological pathways supporting the formation and function of chromatin (Scholarship)
About the Project Every cell in our body contains the same DNA yet each cell expresses a different set of genes. These changes in gene expression are heavily influenced by … Read More Read More
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Tiara Wang-ArmstrongAnalysing the role of statins in cardiovascular protection
Analysing the role of statins in cardiovascular protection
About the Project Drug-induced cardiovascular toxicity is a major problem affecting a number of cancer chemotherapy drugs (Cross et al., 2015). Due to the increasing number of patients treated by … Read More Read More
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Miguel PereiraFree Circulating Histone Variants and Their Complexes in Biofluids as Novel Markers of Diseases
Free Circulating Histone Variants and Their Complexes in Biofluids as Novel Markers of Diseases
About the Project Affiliation: Masaryk University, Faculty of Medicine Study program: PhD program Biomedical Sciences Specialization: Biochemistry and Molecular Biology Workplace: International Clinical Research Center- Center for Translational Medicine (CTM), … Read More Read More
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Isabell BakerTargeting the MAPK scaffold protein KSR1 for the treatment of prostate cancer
Targeting the MAPK scaffold protein KSR1 for the treatment of prostate cancer
About the Project Prostate cancer is one of the leading causes of male cancer deaths. It arises when individual cells escape their normal growth control mechanisms and proliferate in an … Read More Read More
Categories:Nanoparticle synthesis and application in magnetic field hyperthermia for cancer therapy
Nanoparticle synthesis and application in magnetic field hyperthermia for cancer therapy
About the Project Magnetic field hyperthermia (MFH) is currently undergoing clinical trials for use in humans. The research to date has shown the effectiveness of the approach in cells and … Read More Read More
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