The Xu lab at Georgia State University - Fully funded position available
The Xu lab at Georgia State University - Fully funded position available
About the Project The Xu lab focuses on Nanobodies. Nanobodies are antigen-binding entities derived from the heavy chain-only antibodies of camelid animals, and they retain full antigen specificity at a … Read More Read More
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RNA biology: investigating the role of UPF1 in mRNA Processing and Neurodegenerative Diseases
RNA biology: investigating the role of UPF1 in mRNA Processing and Neurodegenerative Diseases
About the Project Accurate gene expression is fundamental to the survival of all life forms. RNA helicases, a large family of enzymes, are key regulators involved in several stages of … Read More Read More
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The role and molecular actions of Galectin-3 in peritoneal fibrosis formation
The role and molecular actions of Galectin-3 in peritoneal fibrosis formation
About the Project Scarring is the abnormal healing process that leads to reduced functionality of a tissue, affecting health and wellbeing. We wish to understand the processes of scarring in … Read More Read More
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Revealing the cellular changes that allow regenerative cell migration.
Revealing the cellular changes that allow regenerative cell migration.
About the Project A central question in the study of regenerative biology is how cells are recruited to sites of injury to allow for tissue regeneration to take place. To … Read More Read More
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Mechanisms of extracellular vesicles derived from human pluripotent stem cells and their cardiac lineage cells for cardiac repair and enhancement of efficacy
Mechanisms of extracellular vesicles derived from human pluripotent stem cells and their cardiac lineage cells for cardiac repair and enhancement of efficacy
About the Project The rising mortality rate of myocardial infarction is due to extensive cell death and remodeling post-infarction. Human pluripotent stem cells (hPSCs) offer repair potential, but transplanted hPSC-derived … Read More Read More
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Understanding the cellular processes which regulate Tetanus and Botulinum toxin intoxication
Understanding the cellular processes which regulate Tetanus and Botulinum toxin intoxication
About the Project Tetanus and Botulinum toxins are potent neurotoxins that are used in a wide number of medical applications from vaccines to neuro-inhibitory based therapeutics. These toxins act by … Read More Read More
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Identify new suppressors of disease-causing proteasome mutations
Identify new suppressors of disease-causing proteasome mutations
About the Project The proteasome degrades most cellular proteins in a controlled and timely manner and thereby controls many key processes. Proteasomes are also essential for maintaining intracellular protein quality … Read More Read More
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Molecular Mechanisms of Cancer Progression
Molecular Mechanisms of Cancer Progression
About the Project The Wells Invasion and Metastasis Research Group is interested in how cancer cells are able to dissociate from the primary tumour, invade the surrounding tissue and subsequently … Read More Read More
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Dynamics of the peri-nuclear actomyosin network for correct chromosome positioning in early mitosis
Dynamics of the peri-nuclear actomyosin network for correct chromosome positioning in early mitosis
About the Project To maintain genetic integrity, human cells must inherit the whole set of chromosomes without any loss or excess when the cell division takes place. To ensure this … Read More Read More
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Targeting amino-acid transporters for treatment of cancer and neurological disorders
Targeting amino-acid transporters for treatment of cancer and neurological disorders
About the Project Metabolism is an important biological process that generate energy for cellular functioning across the body. Brain particularly requires a large amount of energy to perform its complex … Read More Read More
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