Aly HillDeveloping therapies targeting inflammation and dysfunctional matrix biology in neurological and ocular disease
Developing therapies targeting inflammation and dysfunctional matrix biology in neurological and ocular disease
About the Project We are seeking talented, motivated students with a passion for research in inflammation and matrix biology in the eye and brain to join our team co-led by … Read More Read More
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Rebecca Shepherd4-year PhD Studentship: Investigating causal mechanisms between parental social disadvantage and risk of ADHD to the offspring
4-year PhD Studentship: Investigating causal mechanisms between parental social disadvantage and risk of ADHD to the offspring
About the Project Attention Deficit Hyperactivity Disorder (ADHD) is a chronic neurodevelopmental condition, characterised by persistent difficulties in the areas of attention span/impulse control. Approximately 65% of children diagnosed with … Read More Read More
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Kirsten RogdeDisruption of the Connectome in Glioblastomas
Disruption of the Connectome in Glioblastomas
About the Project The invasive behaviour of glioblastomas (the commonest, most malignant primary brain tumour) means that local treatments won’t cure these tumours, and this diffuse invasion means that there … Read More Read More
Categories:Assessing the Effect of Focal Hypoxia in a Microfluidic Neurovascular Unit Chip Model of Small Vessel Diseases (PhD only)
Assessing the Effect of Focal Hypoxia in a Microfluidic Neurovascular Unit Chip Model of Small Vessel Diseases (PhD only)
About the Project Cerebral small vessel disease (cSVD) is the leading cause of vascular dementia, yet there are few effective treatments available. The major challenges in developing new therapies include … Read More Read More
Categories:Ultra-High Field (7T and 11.7T) Magnetic Resonance Imaging (MRI) Development
Ultra-High Field (7T and 11.7T) Magnetic Resonance Imaging (MRI) Development
About the Project I lead the Ultra-High Field MRI Physics group in Cambridge. We create new methods to studying the human brain and body using Cambridge’s state-of-the-art Siemens Terra 7T … Read More Read More
Categories:Multimodal Neuroimaging in Atypical Parkinsonian Disorders
Multimodal Neuroimaging in Atypical Parkinsonian Disorders
About the Project To improve our understanding of the progression of neurodegenerative disease, and the mechanisms involved, we need to combine different types of neuroimaging, and integrate it with clinical … Read More Read More
Categories:Investigating gut-immune interactions in Parkinson’s disease (PhD only
Investigating gut-immune interactions in Parkinson’s disease (PhD only
About the Project It is now well established that both gastrointestinal dysfunction and immune activation occur in early Parkinson’s disease, and emerging evidence indicates that these processes are linked to … Read More Read More
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Tiffany WilliamsAssessing the physical impact of a six-week yoga intervention on brain structure, function, cognition and inflammatory profile in healthy volunteers
Assessing the physical impact of a six-week yoga intervention on brain structure, function, cognition and inflammatory profile in healthy volunteers
About the Project Background The use of yoga and meditation has increased in popularity as a positive health regulator in recent years and has been associated with several beneficial health … Read More Read More
Categories:Investigating Novel Transcription of the X Chromosome and its Role in Developmental Disorders of the Human Brain
Investigating Novel Transcription of the X Chromosome and its Role in Developmental Disorders of the Human Brain
About the Project We hypothesise that annotation of genes and transcripts on the X chromosome is incomplete particularly in the human brain. Furthermore, we hypothesise that this limits our ability … Read More Read More
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Rodrigo OsorioMolecular reclassification of the spectrum of Alzheimer’s disease: Multi-omic, multi-modal models for diagnosis, risk stratification and prognosis prediction
Molecular reclassification of the spectrum of Alzheimer’s disease: Multi-omic, multi-modal models for diagnosis, risk stratification and prognosis prediction
About the Project Commercial partner: CFDX Ltd Neurodegenerative diseases are the 7th leading cause of death globally, and the number one cause of mortality in the UK. The lack of … Read More Read More
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