Unravelling the molecular mechanisms of amyotrophic lateral sclerosis / motor neuron disease
Unravelling the molecular mechanisms of amyotrophic lateral sclerosis / motor neuron disease
About the Project Amyotrophic lateral sclerosis (ALS)—the commonest type of motor neuron disease (MND)—is a rapidly progressive paralysing illness of mid-adulthood. It has a lifetime risk of ~1 in 400, … Read More Read More
Categories:
Phospho-regulation of kinetochore function during mitosis
Phospho-regulation of kinetochore function during mitosis
About the Project Accurate partition of the duplicated genome during cell division is crucial for cellular viability and organismal development. Chromosome mis-segregation is a major source of aneuploidy, and it … Read More Read More
Categories:
Developing an advanced microscopy platform to study protein aggregates in neurons
Developing an advanced microscopy platform to study protein aggregates in neurons
About the Project Department of Brain Sciences at Imperial PhD studentship in advanced fluorescence microscopy to study Parkinson’s disease and dementia with Lewy bodies, Imperial College London Applications are invited … Read More Read More
Categories:
Catalytic nanocages for in situ drug delivery
Catalytic nanocages for in situ drug delivery
About the Project Therapeutic nanoreactors are innovative nanocompartments that confine one or more biocatalysts (e.g., enzymes) for the in-situ production of therapeutic agents, enabling targeted drug delivery with minimal off-site … Read More Read More
Categories:
Sperm derived factors involved in egg activation.
Sperm derived factors involved in egg activation.
About the Project At the fertilization in mammals the sperm initiates a series of Ca2+ oscillations by introducing PLCzeta into the egg. These Ca2+ oscillations activate embryo development. There is … Read More Read More
Categories:
Molecular mechanisms underlying the anti-atherogenic actions of natural products
Molecular mechanisms underlying the anti-atherogenic actions of natural products
About the Project Atherosclerosis, the underlying cause of myocardial infarction, stroke and peripheral vascular disease, is responsible for most deaths in the western world with mortality increasing at a marked … Read More Read More
Categories:
New molecules and mechanisms in angiogenesis
New molecules and mechanisms in angiogenesis
About the Project The School of Molecular & Cellular Biology invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. This … Read More Read More
Categories:
[FSE Bicentenary PhD] Searching for Technosignatures as anomalies in astronomical digital data
[FSE Bicentenary PhD] Searching for Technosignatures as anomalies in astronomical digital data
About the Project The Search for Extraterrestrial Intelligence (SETI) traditionally focuses on detecting technosignatures—observable phenomena indicating the presence of advanced, civilisations. This PhD project aims to develop and apply cutting-edge … Read More Read More
Categories:
[FSE Bicentenary PhD] Beyond AlphaFold: putting the physics back into protein folding
[FSE Bicentenary PhD] Beyond AlphaFold: putting the physics back into protein folding
About the Project One half of the 2024 Nobel prize of Chemistry went to the prediction of protein structure from amino acid sequences. This long-awaited achievement was made possible by … Read More Read More
Categories:
[FSE Bicentenary PhD] Design of Enzymes for Applications in RNA Therapeutics Manufacturing
[FSE Bicentenary PhD] Design of Enzymes for Applications in RNA Therapeutics Manufacturing
About the Project The field of biocatalysis has advanced to the stage where it is now viewed as a key enabling technology for the development of a greener and more … Read More Read More
Categories: